Human health implications of the protoprotector 4-methylbenzylidene camphor (4MBC): a systematic review of endocrine effects
DOI:
https://doi.org/10.55892/jrg.v8i18.2018Keywords:
Sun protection factor, Endocrine disruptors, Hazardous substancesAbstract
4-Methylbenzylidene Camphor (4MBC) is a UV filter that protects humans against sun exposure, helping to prevent skin cancer. However, it has properties that interfere with the endocrine system and other organic systems that are still somewhat unclear. The lack of systematic reviews on the proposed topic is one of the gaps in the literature, as they could contribute to a better analysis of previous studies and probable correlations with endocrine alterations. The study in question aims to develop a literature review for the current understanding of the endocrine effects of 4MBC discovered so far. A structured literature search approach will be used to identify eligible studies related to the effect of 4MBC on the endocrine system. The databases used will be Scielo, PubMed, Oxford Academic and Wiley Online Library. The pre-established descriptors are: 4-methylbenzylidene camphor (4MBC), sunscreens and endocrine disruptors. The exclusion criteria for literature and systematic reviews will be: case studies; book chapters; and overlapping articles. The information and data from the listed articles will be screened and organized by theme for later analysis. It is important to emphasize that the report of this systematic review will follow the recommendations of the PRISMA 2020 Statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), which involves a checklist containing 27 items that must be followed in order to obtain a more transparent, complete, and accurate review, thus facilitating evidence-based decision-making. Regarding the results, it is expected that, with the execution of this project, the relationship between 4-methylbenzylidene camphor and the effects on the endocrine system will be elucidated. The intention is to contribute to the reduction of such negative and unfavorable occurrences caused by the use of sunscreens that contain a toxic substance in their composition.
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