Clinical and laboratory profile of kidney recipients regarding biomarkers of mineral and bone disorders
DOI:
https://doi.org/10.55892/jrg.v8i19.2302Keywords:
transplante de rim, distúrbio mineral e ósseo na doença renal crônica, doença renal crônica, hiperparatireoidismo secundárioAbstract
Kidney transplantation is the ideal therapy for advanced kidney disease, aiming to restore homeostasis of affected systems, such as renal function and bone metabolism. However, after undergoing hyperplasia, the parathyroid glands may undergo reabsorption of calcium from the bones and hypophosphatemia, even after transplantation, requiring continuous monitoring. This is a quantitative and cross-sectional study, carried out from the medical records of kidney transplant patients undergoing outpatient follow-up at a university hospital in Recife-PE, aimed to evaluate the clinical and laboratory conditions of these patients. Data collection included sociodemographic, clinical and laboratory information. Data were analyzed using SPSS version 30.1 software, and data normality was verified by the Shapiro-Wilk test. The study involved 177 medical records, with ages ranging from 21 to 76 years. Most patients were brown (79.1%). Only (8.5%) of the patients had completed higher education. Hypertension was the most common comorbidity (70.6%), and the glomerular filtration rate indicated that most patients were in stage 2 of chronic kidney disease (33%). The diagnosis of hyperparathyroidism was found in few patients (9%). In addition, there was a predominance of patients who were not followed up by the Mineral and Bone Disorders outpatient clinic (91%). It is possible to conclude that the profile of the patients in the study is predominantly male, of mixed race, with a mean age of 50 years and low education. Most received transplant after hemodialysis, with hypertension being the most common comorbidity. Hemodialysis was the most reported renal therapy as a form of treatment and laboratory tests indicated high levels of phosphorus, creatinine and parathyroid hormone.
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