Effect of curative chemotherapy on nutritional status and gastrointestinal symptoms

Authors

DOI:

https://doi.org/10.55892/jrg.v8i19.2659

Keywords:

antineoplastic agents, nutrition assessment, signs and symptoms, neoplasms, malnutrition

Abstract

Objective: This study aims to evaluate the effect of curative chemotherapy on nutritional status and gastrointestinal symptoms in adult and elderly patients. Method: This is a cross-sectional observational study, with data collection carried out from January to May 2025 at the Hospital de Base do Distrito Federal. An anamnesis was applied using a specific form, the NRS-2002 screening tool was used, and the ASG-PPP tool was used to assess nutritional status and gastrointestinal symptoms. Results: Information was collected from 85 people, of whom 90.5% (n=77) presented some weight loss, ranging from moderate to severe. Individuals were classified into groups A, B, and C, being respectively well-nourished, moderately malnourished, and severely malnourished. In group C, there was greater weight loss (22.5 kg ± 9.8), as well as lower values ​​for calf and arm circumference. Thirteen symptoms were evaluated in patients undergoing chemotherapy, with the highest prevalence of hyporexia (54%; n=47), nausea (50%; n=43), dysgeusia (37%; n=32), and xerostomia (37%; n=32). The presence of symptoms was higher in group C, the severely malnourished. Conclusion: Most individuals presented severe weight loss, placing them at nutritional risk. The most prevalent symptoms were hyporexia, nausea, dysgeusia, and xerostomia. Individuals classified as severely malnourished presented greater weight loss, greater muscle mass depletion, lower circumference values, and a greater association with the symptoms when compared to the other groups.

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Author Biographies

Bárbara Queiroz Fernandes, FEPECS, DF, Brasil

Graduada em nutrição pela Universidade do Distrito Federal. Pós-graduanda no Programa de Residência Multiprofissional em Atenção Oncológica pela Fundação de Ensino e Pesquisa em Ciências da Saúde (Brasília-DF)

Brenda de Oliveira Carvalho do Vale, FEPECS, DF, Brasil

Graduada em nutrição pelo CEUB. Especialista em saúde do adulto e idoso pela ESCS/FEPECS. Pós-graduanda no Programa de Residência Multiprofissional em Atenção Oncológica pela Fundação de Ensino e Pesquisa em Ciências da Saúde (Brasília-DF)

Fernanda Cintra Lima, Secretaria de Saúde do Distrito Federal, DF, Brasil

Graduada em Nutrição pela Universidade de Brasília. Mestre em Ciências da Saúde pela Escola Superior de Ciências da Saúde.

Anna Carla Lima Camargo, Hospital de Base, DF, Brasil

Graduada em Ciências Biológicas pela Universidade de Brasília. Mestre em Ecologia pela Universidade de Brasília.

Leandresson Pires Reis, FEPECS, DF, Brasil

Graduado em Nutrição pelo Centro Universitário Mauá de Brasília. Especialista em Atenção Cardíaca pela FEPECS.

Marcela Monteiro da Silva, FEPECS, DF, Brasil

Graduada em Nutrição pelo Centro Universitário do Planalto Central Apparecido dos Santos. Pós-graduanda do Programa de Residência Multiprofissional de Urgência e Trauma pela Fundação de Ensino e Pesquisa em Ciências da Saúde (Brasília-DF).

Amanda Karen Ferreira Barbosa, FEPECS, DF, Brasil

Graduada em Nutrição pela Universidade de Brasília. Pós-graduanda do Programa de Residência Multiprofissional de Urgência e Trauma pela Fundação de Ensino e Pesquisa em Ciências da Saúde (Brasília-DF).

Natália Fernandes de Figueiredo, FEPECS, DF, Brasil

Graduada em Nutrição pela Universidade de Brasília. Pós-graduanda do Programa de Residência Multiprofissional em Terapia Intensiva pela Fundação de Ensino e Pesquisa em Ciências da Saúde (Brasília-DF).

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Published

2025-11-12

How to Cite

FERNANDES, B. Q.; VALE, B. de O. C. do; LIMA, F. C.; CAMARGO, A. C. L.; REIS, L. P.; SILVA, M. M. da; BARBOSA, A. K. F.; FIGUEIREDO, N. F. de. Effect of curative chemotherapy on nutritional status and gastrointestinal symptoms. JRG Journal of Academic Studies, Brasil, São Paulo, v. 8, n. 19, p. e082659, 2025. DOI: 10.55892/jrg.v8i19.2659. Disponível em: https://www.revistajrg.com/index.php/jrg/article/view/2659. Acesso em: 16 nov. 2025.

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